Delayed inactivation of Citrobacter freundii cephalosporinase by 6.BETA.-(3-(2-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin sulfone.
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منابع مشابه
Delayed inactivation of Citrobacter freundii cephalosporinase by 6 beta-[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]penicillin sulfone.
When Citrobacter freundii cephalosporinase was incubated with 6 beta-[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]penicillin sulfone (cloxacillin sulfone) in phosphate buffer, the enzyme was suddenly inactivated just after the completion of enzymatic degradation of the cloxacillin sulfone. Such delayed inactivation was due to a secondary inhibitor formed from cloxacillin sulfone during the incubat...
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In the title compound, C(23)H(17)ClN(4)O(2), the amino H atom forms an intra-molecular hydrogen bond to the exocyclic carbonyl O atom as well as to the O atom of the benzoyl group.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1986
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.39.1744